Systematic analysis of Fc mutations designed to enhance binding to Fc-gamma receptors

A critical attribute of therapeutic antibodies is their ability to engage with humoral or cellular effector mechanisms, and this depends on the ability of the Fc region to bind to complement (C1q) or Fc receptors. Investigators have sought to optimize these effects by engineering the Fc region to bi...

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Bibliographic Details
Main Authors: Geoff Hale (Author), Alastair Douglas Davy (Author), Ian Wilkinson (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available