Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana.

• Main Authors: Franca C Hartgers (Author), Benedicta B Obeng (Author), Yvonne C M Kruize (Author), Marjolijn Duijvestein (Author), Anna de Breij (Author), Abena Amoah (Author), Irene A Larbi (Author), Ronald van Ree (Author), Michael D Wilson (Author), Laura C Rodrigues (Author), Daniel A Boakye (Author), Maria Yazdanbakhsh (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Helminth infections are prevalent in rural areas of developing countries and have in some studies been negatively associated with allergic disorders and atopy. In this context little is known of the molecular mechanisms of modulation involved. We have characterized the innate immune responses, at th...