Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis

• Main Authors: Jianghu Zhou (Author), Fengjun Lan (Author), Miao Liu (Author), Fengyan Wang (Author), Xu Ning (Author), Hua Yang (Author), Hong Sun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma (OS) is a malignant tumor originating from mesenchymal tissue. Pulmonary metastasis is usually present upon initial diagnosis, and metastasis is the primary factor affecting the poor prognosis of patients with OS. Current research shows that the ability to regulate the cellular microenv...