A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM

• Main Authors: Gledys Reynaldo (Author), Leyanis Rodríguez (Author), Roberto Menéndez (Author), Joaquín Solazábal (Author), Daniel Amaro (Author), María de los A. Becquer (Author), Yamila Colom (Author), Haydee Gil (Author), Juan C. Polo (Author), Gilberto Castañeda (Author), Braulio Jiménez-Vélez (Author), Jorge Duconge (Author), Eduardo M. Fernández-Sánchez (Author)
• Format: Book
• Published: GarVal Editorial Ltda., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: The recombinant human erythropoietin (rHuEPO) stimulates the erythropoiesis process. Because this glycoprotein has a short half-life, it needs to be administrated two to three times a week. One of the technics to solve this issue is the PEGgilation. Aims: To evaluate the pharmacokinetics (P...