Aripiprazole sensitizes head and neck cancer cells to ionizing radiation by enhancing the production of reactive oxygen species

• Main Authors: Hyeon‐Jeong Jeong (Author), Chan‐Woong Jung (Author), Hee‐Jin Kim (Author), Byunghee Park (Author), Youna Moon (Author), Jeong‐Yub Kim (Author), Myung‐Jin Park (Author)
• Format: Book
• Published: Wiley, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Drug repositioning is an alternative process for drug development in cancer. Specifically, it is a strategy for the discovery of new antitumor drugs by screening previously approved clinical drugs. On the basis of this strategy, aripiprazole, an antipsychotic drug, was found to have antican...