Preclinical metabolism and metabolic drug-drug interaction profile of pedunculoside and rotundic acid

• Main Authors: Liang Wu (Author), Linling Dong (Author), Zhu Zhou (Author), Xin Wang (Author), Yujie Lin (Author), Xuesong Shi (Author), Peijing Wang (Author), Suocheng Xu (Author), Zhiyi Fang (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pedunculoside and rotundic acid, the most abundant components in plants of the genus Ilex L. (Aquifoliaceae), exhibit biological and pharmacological significance in the treatment of cardiovascular diseases. However, there have been few studies on their metabolism. This study performed a sys...