Concurrent silencing of TBCE and drug delivery to overcome platinum-based resistance in liver cancer

• Main Authors: Senlin Li (Author), Siyu Chen (Author), Zhihui Dong (Author), Xingdong Song (Author), Xiuling Li (Author), Ziqi Huang (Author), Huiru Li (Author), Linzhuo Huang (Author), Ganyuan Zhuang (Author), Ran Lan (Author), Mingyan Guo (Author), Wende Li (Author), Phei Er Saw (Author), Lei Zhang (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Platinum-based chemotherapy resistance is a key factor of poor prognosis and recurrence in hepatocellular carcinoma (HCC). Herein, RNAseq analysis revealed that elevated tubulin folding cofactor E (TBCE) expression is associated with platinum-based chemotherapy resistance. High expression of TBCE co...