Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury

• Main Authors: Duncan C. Humphries (Author), Ross Mills (Author), Ross Dobie (Author), Neil C. Henderson (Author), Tariq Sethi (Author), Alison C. Mackinnon (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rationale: Galectin-3 (Gal-3) is an immune regulator and an important driver of fibrosis in chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Previous work has shown that global deletion of galectin-3 reduces collagen deposition in a bleomycin-induced pulmonary fibro...