Mitochondria-Targeted Antioxidants as a Therapeutic Strategy for Chronic Obstructive Pulmonary Disease

• Κύριοι συγγραφείς: Lauren H. Fairley (Συγγραφέας), Shatarupa Das (Συγγραφέας), Vivek Dharwal (Συγγραφέας), Nadia Amorim (Συγγραφέας), Karl J. Hegarty (Συγγραφέας), Ridhima Wadhwa (Συγγραφέας), Guntipally Mounika (Συγγραφέας), Philip M. Hansbro (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2023-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Oxidative stress is a major hallmark of COPD, contributing to inflammatory signaling, corticosteroid resistance, DNA damage, and accelerated lung aging and cellular senescence. Evidence suggests that oxidative damage is not solely due to exogenous exposure to inhaled irritants, but also endogenous s...