In vivo SELEX for Identification of Brain-penetrating Aptamers

• 主要な著者: Congsheng Cheng (著者), Yong Hong Chen (著者), Kim A Lennox (著者), Mark A Behlke (著者), Beverly L Davidson (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2013-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The physiological barriers of the brain impair drug delivery for treatment of many neurological disorders. One delivery approach that has not been investigated for their ability to penetrate the brain is RNA-based aptamers. These molecules can impart delivery to peripheral tissues and circulating im...