Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer

• Prif Awduron: Hyo Jeong Lee (Awdur), Pyeonghwa Jeong (Awdur), Yeongyu Moon (Awdur), Jungil Choi (Awdur), Jeong Doo Heo (Awdur), Yong-Chul Kim (Awdur), Sun-Young Han (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2021-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Rearranged during transfection (RET), a receptor tyrosine kinase, is activated by glial cell line-derived neurotrophic factor family ligands. Chromosomal rearrangement or point mutations in <i>RET</i> are observed in patients with papillary thyroid and medullary thyroid carcinomas. Oncog...