The distinct role of kappa opioid receptor in attenuating relapse to morphine/methamphetamine (polydrug) dependence in mice

• Main Authors: Irna Elina Ridzwan (Author), Maryam Saadah Suhaimi (Author), Nur Syafinaz Wasli (Author), Abdul Razak Kasmuri (Author), Marwan Saad Azzubaidi (Author), Ridzwan Hashim (Author), Qamar Uddin Ahmed (Author), Long Chiau Ming (Author), Nornisah Mohamed (Author), Syed Mohd Syhami (Author)
• Format: Book
• Published: University of Huddersfield Press, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A Combination of 0.3mg/kg buprenorphine and 1.0 mg/kg naltrexone treatment shows a promising result due to its ability to attenuate reinstatement (relapse) in morphine/methamphetamine (polydrug)-dependent mice in a conditioned place preference (CPP) model. This prompted us to identify which opioid r...