Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR

• Main Authors: Maud Mavigner (Author), S. Thera Lee (Author), Jakob Habib (Author), Cameron Robinson (Author), Guido Silvestri (Author), Una O'Doherty (Author), Ann Chahroudi (Author)
• Format: Book
• Published: Elsevier, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Although antiretroviral therapy (ART) effectively suppresses HIV-1 replication, it does not eradicate the virus and ART interruption consistently results in rebound of viraemia, demonstrating the persistence of a long-lived viral reservoir. Several approaches aimed at reducing virus pers...