Approaches to Assure Similarity between Pharmaceutical Heparins from Two Different Manufacturers

• Main Authors: Francisco Felipe Bezerra (Author), Stephan N.M.C.G. Oliveira (Author), Rodrigo A. Sales (Author), Adriana A. Piquet (Author), Nina V. Capillé (Author), Eduardo Vilanova (Author), Ana M.F. Tovar (Author), Paulo A.S. Mourão (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmaceutical heparins from different manufacturers may present heterogeneities due to particular extraction and purification procedures or even variations in the raw material manipulation. Heparins obtained from different tissues also differ in their structure and activity. Nevertheless, there is...