Spatial Memory Impairment Without Apoptosis Induced by the Combination of Beta-Amyloid Oligomers and Cerebral Ischemia Is Related to Decreased Acetylcholine Release in Rats

• मुख्य लेखकों: Takuya Watanabe (लेखक), Katsunori Iwasaki (लेखक), Shin Ishikane (लेखक), Tetsuya Naitou (लेखक), Yoshitaka Yoshimitsu (लेखक), Norito Yamagata (लेखक), Mehmeto Bülent Ozdemir (लेखक), Kotaro Takasaki (लेखक), Nobuaki Egashira (लेखक), Kenichi Mishima (लेखक), Michihiro Fujiwara (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2008-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The purpose of the present study was to examine the effect of beta-amyloid (Aβ ) oligomers, not the fibrils that make up Aβ plaques, on spatial memory and the cholinergic system in rats. Recently, several researchers have suggested that small assemblies of Aβ, Aβ oligomers, caused memory loss during...