Spatial Memory Impairment Without Apoptosis Induced by the Combination of Beta-Amyloid Oligomers and Cerebral Ischemia Is Related to Decreased Acetylcholine Release in Rats

• প্রধান লেখক: Takuya Watanabe (লেখক), Katsunori Iwasaki (লেখক), Shin Ishikane (লেখক), Tetsuya Naitou (লেখক), Yoshitaka Yoshimitsu (লেখক), Norito Yamagata (লেখক), Mehmeto Bülent Ozdemir (লেখক), Kotaro Takasaki (লেখক), Nobuaki Egashira (লেখক), Kenichi Mishima (লেখক), Michihiro Fujiwara (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2008-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The purpose of the present study was to examine the effect of beta-amyloid (Aβ ) oligomers, not the fibrils that make up Aβ plaques, on spatial memory and the cholinergic system in rats. Recently, several researchers have suggested that small assemblies of Aβ, Aβ oligomers, caused memory loss during...