β-Elemene promotes ferroptosis and reverses radioresistance in gastric cancer by inhibiting the OTUB1-GPX4 interaction

• Main Authors: Jiancheng He (Author), Ming Li (Author), Jiapeng Bao (Author), Yifeng Peng (Author), Wanjiang Xue (Author), Junjie Chen (Author), Jun Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introductionβ-Elemene, derived from Curcuma zedoaria (Wenyujin), is clinically recognized for inducing apoptosis, inhibiting cell cycle progression, and reversing chemotherapy resistance in various cancers. However, its effects on radioresistant gastric cancer (GC) remain unclear.MethodsIn this stud...