Increased BMPR1A Expression Enhances the Adipogenic Differentiation of Mesenchymal Stem Cells in Patients with Ankylosing Spondylitis

• Main Authors: Zhenhua Liu (Author), Peng Wang (Author), Shuizhong Cen (Author), Liangbin Gao (Author), Zhongyu Xie (Author), Xiaohua Wu (Author), Hongjun Su (Author), Yanfeng Wu (Author), Huiyong Shen (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To investigate the adipogenic differentiation capacity of mesenchymal stem cells (MSCs) from ankylosing spondylitis (AS) patients and explore the mechanism of abnormal MSC adipogenesis in AS. Methods. MSCs from patients with AS (ASMSCs) and healthy donors (HDMSCs) were cultured in adipoge...