Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding

• Egile Nagusiak: Yanaika Shari Sabogal Piñeros (Egilea), Tamara Dekker (Egilea), Barbara Smids (Egilea), Christof J. Majoor (Egilea), Lara Ravanetti (Egilea), Gino Villetti (Egilea), Maurizio Civelli (Egilea), Fabrizio Facchinetti (Egilea), René Lutter (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2020-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate respiratory viruses. Phosphodiesterase t...