N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production

• Asıl Yazarlar: Parmanand Malvi (Yazar), Radoslav Janostiak (Yazar), Arvindhan Nagarajan (Yazar), Xuchen Zhang (Yazar), Narendra Wajapeyee (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: Metabolic deregulation is a key hallmark of cancer cells and has been shown to drive cancer growth and metastasis. However, not all metabolic drivers of melanoma are known. Based on our finding that N-acylsphingosine amidohydrolase 1 (ASAH1) is overexpressed in melanoma, the objective of...