Unveiling the contribution of tumor-associated macrophages in driving epithelial-mesenchymal transition: a review of mechanisms and therapeutic Strategies

• Hoofdauteurs: Yijia Zhang (Auteur), Xiaofei Ding (Auteur), Xue Zhang (Auteur), Ye Li (Auteur), Rui Xu (Auteur), Hai-Jun Li (Auteur), Daiying Zuo (Auteur), Guang Chen (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Tumor-associated macrophages (TAMs), fundamental constituents of the tumor microenvironment (TME), significantly influence cancer development, primarily by promoting epithelial-mesenchymal transition (EMT). EMT endows cancer cells with increased motility, invasiveness, and resistance to therapies, m...