Unveiling the contribution of tumor-associated macrophages in driving epithelial-mesenchymal transition: a review of mechanisms and therapeutic Strategies

• Autors principals: Yijia Zhang (Autor), Xiaofei Ding (Autor), Xue Zhang (Autor), Ye Li (Autor), Rui Xu (Autor), Hai-Jun Li (Autor), Daiying Zuo (Autor), Guang Chen (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Tumor-associated macrophages (TAMs), fundamental constituents of the tumor microenvironment (TME), significantly influence cancer development, primarily by promoting epithelial-mesenchymal transition (EMT). EMT endows cancer cells with increased motility, invasiveness, and resistance to therapies, m...