Identification of Potential <i>Trypanosoma cruzi</i> Trans-Sialidase Inhibitors by Computational Drug Repositioning Approaches

• Glavni autori: Miguel A. Uc-Chuc (Autor), Nohemi Cigarroa-Toledo (Autor), Karla Y. Acosta-Viana (Autor), José I. Chan-Pérez (Autor), Juan C. Pineda-Cortes (Autor), Hernán de J. Villanueva-Alonzo (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2024-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Chagas disease, caused by the parasitic protozoan <i>Trypanosoma cruzi</i> (<i>T. cruzi</i>), represents a worldwide public health issue. To date, there is no efficient treatment to combat this pathology, and the only drugs available are usually toxic to the patient. Through...