Identification of Potential <i>Trypanosoma cruzi</i> Trans-Sialidase Inhibitors by Computational Drug Repositioning Approaches

• Main Authors: Miguel A. Uc-Chuc (Author), Nohemi Cigarroa-Toledo (Author), Karla Y. Acosta-Viana (Author), José I. Chan-Pérez (Author), Juan C. Pineda-Cortes (Author), Hernán de J. Villanueva-Alonzo (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease, caused by the parasitic protozoan <i>Trypanosoma cruzi</i> (<i>T. cruzi</i>), represents a worldwide public health issue. To date, there is no efficient treatment to combat this pathology, and the only drugs available are usually toxic to the patient. Through...