Influence of the Microenvironment in the Transcriptome of Leishmania infantum Promastigotes: Sand Fly versus Culture.

• Main Authors: Pedro J Alcolea (Author), Ana Alonso (Author), Mercedes Domínguez (Author), Víctor Parro (Author), Maribel Jiménez (Author), Ricardo Molina (Author), Vicente Larraga (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zoonotic visceral leishmaniasis is a vector-borne disease caused by Leishmania infantum in the Mediterranean Basin, where domestic dogs and wild canids are the main reservoirs. The promastigote stage replicates and develops within the gut of blood-sucking phlebotomine sand flies. Mature promastigote...