Gene-Based Association Analysis Suggests Association of HTR2A With Antidepressant Treatment Response in Depressed Patients

• Main Authors: Chung-Feng Kao (Author), Po-Hsiu Kuo (Author), Younger W.-Y. Yu (Author), Albert C. Yang (Author), Eugene Lin (Author), Yu-Li Liu (Author), Shih-Jen Tsai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The serotonin [5-hydroxytryptamine (5-HT)] system has been implicated in the pathogenesis of major depressive disorder (MDD). Among the 5-HT receptor subtypes, 5-HT2 is one of the major pharmacological therapeutic targets for MDD. There have been inconsistent findings in previous pharmacogenetic stu...