S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling

• Main Authors: Ashok Kumar (Author), Jesus Zamora-Pineda (Author), Emilie Degagné (Author), Julie D. Saba (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sphingosine-1-phosphate (S1P) is a potent lipid signaling molecule that regulates pleiotropic biological functions including cell migration, survival, angiogenesis, immune cell trafficking, inflammation, and carcinogenesis. It acts as a ligand for a family of cell surface receptors. S1P concentratio...