Aspirin Attenuates Cardiac Allograft Rejection by Inhibiting the Maturation of Dendritic Cells via the NF-κB Signaling Pathway

• Main Authors: Xi Zhang (Author), Aie Chang (Author), Yanqiang Zou (Author), Heng Xu (Author), Jikai Cui (Author), Zhang Chen (Author), Yuan Li (Author), Yifan Du (Author), Jie Wu (Author), Jizhang Yu (Author), Xinling Du (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Dendritic cells (DCs) serve as an important part of the immune system and play a dual role in immune response. Mature DCs can initiate immune response, while immature or semi-mature DCs induce immune hyporesponsiveness or tolerance. Previous studies have shown that aspirin can effectivel...