miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation

• Main Authors: Michela Simbula (Author), Maria Francesca Manchinu (Author), Maura Mingoia (Author), Mauro Pala (Author), Isadora Asunis (Author), Cristian Antonio Caria (Author), Lucia Perseu (Author), Manan Shah (Author), Merlin Crossley (Author), Paolo Moi (Author), Maria Serafina Ristaldi (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hemoglobin switching is a complex biological process not yet fully elucidated. The mechanism regulating the suppression of fetal hemoglobin (HbF) expression is of particular interest because of the positive impact of HbF on the course of diseases such as β-thalassemia and sickle cell disease, heredi...