Pyrogens Enhance β-Endorphin Release in Hypothalamus and Trigger Fever That Can Be Attenuated by Buprenorphine

• Egile Nagusiak: Shu-Ming Tsai (Egilea), Mao-Tsun Lin (Egilea), Jhi-Joung Wang (Egilea), Wu-Tein Huang (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2003-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

ABSTRACT: At first, we investigated whether both β-endorphin release level in the hypothalamus and body temperature can be altered after intracerebroventricular (i.c.v.) injection of either lipopolysaccharide (LPS), interleukin-1β (IL-1β), or prostaglandin E2 (PGE2) in rats. It was found that in the...