Isoniazid-historical development, metabolism associated toxicity and a perspective on its pharmacological improvement

Despite the extraordinary anti-tubercular activity of isoniazid (INH), the drug-induced hepatotoxicity and peripheral neuropathy pose a significant challenge to its wider clinical use. The primary cause of INH-induced hepatotoxicity is in vivo metabolism involving biotransformation on its terminal -...

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Main Authors: Jishnu Sankar (Author), Anjali Chauhan (Author), Ramandeep Singh (Author), Dinesh Mahajan (Author)
Format: Book
Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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