Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system

• Main Authors: Nan Wu (Author), Yaqin Tu (Author), Guorun Fan (Author), Jiahui Ding (Author), Jun Luo (Author), Wei Wang (Author), Chong Zhang (Author), Caiyan Yuan (Author), Handan Zhang (Author), Pei Chen (Author), Songwei Tan (Author), Hongjun Xiao (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The hypoxic nature of tumours limits the efficiency of oxygen-dependent photodynamic therapy (PDT). Hence, in this study, indocyanine green (ICG)-loaded lipid-coated zinc peroxide (ZnO2) nanoparticles (ZnO2@Lip-ICG) was constructed to realize tumour microenvironment (TME)-responsive self-oxygen supp...