TIMP1 preserves the blood-brain barrier through interacting with CD63/integrin β1 complex and regulating downstream FAK/RhoA signaling

Blood-brain barrier (BBB) breakdown and the associated microvascular hyperpermeability are hallmark features of several neurological disorders, including traumatic brain injury (TBI). However, there is no viable therapeutic strategy to rescue BBB function. Tissue inhibitor of metalloproteinase-1 (TI...

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Hoofdauteurs: Jingshu Tang (Auteur), Yuying Kang (Auteur), Longjian Huang (Auteur), Lei Wu (Auteur), Ying Peng (Auteur)
Formaat: Boek
Gepubliceerd in: Elsevier, 2020-06-01T00:00:00Z.
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