Evaluation of the Ejection Pressure for Tracking Internal Cracks during Compaction in Bilayer Tablet Formulations Using Experimental and Finite Element Methods

• मुख्य लेखकों: Sun Ho Kim (लेखक), Su Hyeon Han (लेखक), Jong-Seok Oh (लेखक), Dong-Wan Seo (लेखक), Myung Joo Kang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study aimed to evaluate the ejection pressure and the correlation of the findings with the occurrence of internal cracks within bilayer tablets (BLTs) consisting of metformin HCl (MF) and evogliptin tartrate (EG). Then, the mechanism of tablet failure was provided by the finite element method (...