Evaluation of the Ejection Pressure for Tracking Internal Cracks during Compaction in Bilayer Tablet Formulations Using Experimental and Finite Element Methods

This study aimed to evaluate the ejection pressure and the correlation of the findings with the occurrence of internal cracks within bilayer tablets (BLTs) consisting of metformin HCl (MF) and evogliptin tartrate (EG). Then, the mechanism of tablet failure was provided by the finite element method (...

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Main Authors: Sun Ho Kim (Author), Su Hyeon Han (Author), Jong-Seok Oh (Author), Dong-Wan Seo (Author), Myung Joo Kang (Author)
Format: Book
Published: MDPI AG, 2024-03-01T00:00:00Z.
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