Sigma-1 receptor exerts protective effects on ameliorating nephrolithiasis by modulating endoplasmic reticulum-mitochondrion association and inhibiting endoplasmic reticulum stress-induced apoptosis in renal tubular epithelial cells

• Main Authors: Hu Ke (Author), Xiaozhe Su (Author), Caitao Dong (Author), Ziqi He (Author), Qianlin Song (Author), Chao song (Author), Jiawei Zhou (Author), Wenbiao Liao (Author), Chuan Wang (Author), Sixing Yang (Author), Yunhe Xiong (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxalate-induced damage to renal tubular epithelial cells (RTECs) is an essential factor in the incident kidney stone, but the specific mechanism is unclear. Recent research has pinpointed interacting areas within the endoplasmic reticulum and mitochondria, called mitochondria-associated membranes (M...