Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense.

• Main Authors: Mario Waespy (Author), Thaddeus T Gbem (Author), Leroy Elenschneider (Author), André-Philippe Jeck (Author), Christopher J Day (Author), Lauren Hartley-Tassell (Author), Nicolai Bovin (Author), Joe Tiralongo (Author), Thomas Haselhorst (Author), Sørge Kelm (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fourteen different active Trypanosoma congolense trans-sialidases (TconTS), 11 variants of TconTS1 besides TconTS2, TconTS3 and TconTS4, have been described. Notably, the specific transfer and sialidase activities of these TconTS differ by orders of magnitude. Surprisingly, phylogenetic analysis of...