Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth.

• Main Authors: Wing-Hong Kwan (Author), Erika Navarro-Sanchez (Author), Hélène Dumortier (Author), Marion Decossas (Author), Hortense Vachon (Author), Flavia Barreto dos Santos (Author), Hervé W Fridman (Author), Félix A Rey (Author), Eva Harris (Author), Philippe Despres (Author), Christopher G Mueller (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: An important question in dengue pathogenesis is the identity of immune cells involved in the control of dengue virus infection at the site of the mosquito bite. There is evidence that infection of immature myeloid dendritic cells plays a crucial role in dengue pathogenesis and that the i...