Liquid-phase oxidation of 2-chlorotoluene with ozone to 2-chlorobenzoic acid - an intermediate for diclofenac sodium production

2-Chlorobenzoic acid is used as an intermediate for diclofenac sodium production. In industry, it is obtained by oxidation of 2-chlorotoluene with potassium permanganate in an aqueous acidic medium. Due to the deficiency and cost of the oxidant as well as the formation of large amounts of toxic wast...

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Main Authors: A. S. Bushuiev (Author), A. H. Halstian (Author), V. V. Kotova (Author)
Format: Book
Published: Zaporozhye State Medical University, 2020-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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