Liquid-phase oxidation of 2-chlorotoluene with ozone to 2-chlorobenzoic acid - an intermediate for diclofenac sodium production
2-Chlorobenzoic acid is used as an intermediate for diclofenac sodium production. In industry, it is obtained by oxidation of 2-chlorotoluene with potassium permanganate in an aqueous acidic medium. Due to the deficiency and cost of the oxidant as well as the formation of large amounts of toxic wast...
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Zaporozhye State Medical University,
2020-11-01T00:00:00Z.
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A1234.567 |
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