Liquid-phase oxidation of 2-chlorotoluene with ozone to 2-chlorobenzoic acid - an intermediate for diclofenac sodium production

• मुख्य लेखकों: A. S. Bushuiev (लेखक), A. H. Halstian (लेखक), V. V. Kotova (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Zaporozhye State Medical University, 2020-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

2-Chlorobenzoic acid is used as an intermediate for diclofenac sodium production. In industry, it is obtained by oxidation of 2-chlorotoluene with potassium permanganate in an aqueous acidic medium. Due to the deficiency and cost of the oxidant as well as the formation of large amounts of toxic wast...