Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT3 Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats

• Những tác giả chính: Rafał Kossakowski (Tác giả), Eberhard Schlicker (Tác giả), Marek Toczek (Tác giả), Jolanta Weresa (Tác giả), Barbara Malinowska (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Cannabidiol (CBD) is a nonpsychotropic constituent of Cannabis sativa L. It is suggested to be useful in hypertension. Under in vitro conditions, it activates vanilloid TRPV1 and inhibits serotonin 5-HT3 receptors, i.e., receptors involved in the Bezold-Jarisch reflex stimulation. The aim of our stu...