JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors

Abstract Background Rheumatoid arthritis (RA) is characterized by chronic inflammation and resultant cartilage/bone destruction because of aberrantly activated osteoclasts. Recently, novel treatments with several Janus kinase (JAK) inhibitors have been shown to successfully ameliorate arthritis-rela...

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Main Authors: Shinya Yari (Author), Junichi Kikuta (Author), Hotaka Shigyo (Author), Yu Miyamoto (Author), Daisuke Okuzaki (Author), Yuki Furusawa (Author), Masafumi Minoshima (Author), Kazuya Kikuchi (Author), Masaru Ishii (Author)
Format: Book
Published: BMC, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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