JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors
Abstract Background Rheumatoid arthritis (RA) is characterized by chronic inflammation and resultant cartilage/bone destruction because of aberrantly activated osteoclasts. Recently, novel treatments with several Janus kinase (JAK) inhibitors have been shown to successfully ameliorate arthritis-rela...
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Main Authors: | Shinya Yari (Author), Junichi Kikuta (Author), Hotaka Shigyo (Author), Yu Miyamoto (Author), Daisuke Okuzaki (Author), Yuki Furusawa (Author), Masafumi Minoshima (Author), Kazuya Kikuchi (Author), Masaru Ishii (Author) |
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Format: | Book |
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BMC,
2023-03-01T00:00:00Z.
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