Development of a Library of Disulfide Bond-Containing Cationic Lipids for mRNA Delivery

• मुख्य लेखकों: Zhigao Shen (लेखक), Cong Liu (लेखक), Ziqian Wang (लेखक), Fengfei Xie (लेखक), Xingwu Liu (लेखक), Lingkai Dong (लेखक), Xuehua Pan (लेखक), Chen Zeng (लेखक), Peng George Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Lipid nanoparticles (LNPs) are the commonly used delivery tools for messenger RNA (mRNA) therapy and play an indispensable role in the success of COVID-19 mRNA vaccines. Ionizable cationic lipids are the most important component in LNPs. Herein, we developed a series of new ionizable lipids featurin...