Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat

• Main Authors: Marchand Fabien (Author), D'Mello Richard (Author), Yip Ping K (Author), Calvo Margarita (Author), Muller Emilie (Author), Pezet Sophie (Author), Dickenson Anthony H (Author), McMahon Stephen B (Author)
• Format: Book
• Published: SAGE Publishing, 2011-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Central sensitization requires the activation of various intracellular signalling pathways within spinal dorsal horn neurons, leading to a lowering of activation threshold and enhanced responsiveness of these cells. Such plasticity c...