Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation

• Main Authors: Maria Camilla Operti (Author), Alexander Bernhardt (Author), Vladimir Sincari (Author), Eliezer Jager (Author), Silko Grimm (Author), Andrea Engel (Author), Martin Hruby (Author), Carl Gustav Figdor (Author), Oya Tagit (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the efficacy and potential therapeutic benefits that poly(lactic-co-glycolic acid) (PLGA) nanomedicine formulations can offer, challenges related to large-scale processing hamper their clinical and commercial development. Major hurdles for the launch of a polymeric nanocarrier product on the...