Quercetin and Isorhamnetin Attenuate Benzo[a]pyrene-Induced Toxicity by Modulating Detoxification Enzymes through the AhR and NRF2 Signaling Pathways

• Main Authors: Min Kim (Author), Seung-Cheol Jee (Author), Kyeong-Seok Kim (Author), Hyung-Sik Kim (Author), Kyoung-Nae Yu (Author), Jung-Suk Sung (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2021-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Benzo[a]pyrene, classified as a Group 1 carcinogen, is metabolized to B[a]P-7,8-dihydrodiol-9,10-epoxide (BPDE), causing DNA mutations and eventually cancer. Quercetin is a dietary flavonoid abundant in fruits and vegetables. After quercetin intake, quercetin's metabolites isorhamnetin and miqu...