Enhanced Oral Bioavailability of MT-102, a New Anti-inflammatory Agent, via a Ternary Solid Dispersion Formulation

• Main Authors: Rajiv Bajracharya (Author), Jae Geun Song (Author), Sang Hoon Lee (Author), Seong Hoon Jeong (Author), Hyo-Kyung Han (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to develop a solid dispersion (SD) of MT-102, a new anti-inflammatory agent, to improve its oral bioavailability. The ternary SD formulations of MT-102 (a poorly soluble extract of <i>Isatis indigotica</i> and <i>Juglans mandshurica</i>) were prepared using a...