Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats

• Hauptverfasser: Rae Man Kim (Verfasst von), Dong-Jin Jang (Verfasst von), Yu Chul Kim (Verfasst von), Jin-Ha Yoon (Verfasst von), Kyoung Ah Min (Verfasst von), Han-Joo Maeng (Verfasst von), Kwan Hyung Cho (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2018-11-01T00:00:00Z.
• Schlagworte: article
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The aim of this work was to prepare and optimize a solid self-nanoemulsifying drug delivery system pre-concentrate (SSP) containing water-insoluble flurbiprofen (FL) using a novel pseudo-ternary phase diagram. The pseudo-ternary phase diagram, composed of FL as the drug and dispersion core, Kollisol...