Population pharmacokinetics and limited sampling strategy for therapeutic drug monitoring of mycophenolate mofetil in Japanese patients with lupus nephritis

• Prif Awduron: Tomoko Mizaki (Awdur), Hironobu Nobata (Awdur), Shogo Banno (Awdur), Makoto Yamaguchi (Awdur), Hiroshi Kinashi (Awdur), Shiho Iwagaitsu (Awdur), Takuji Ishimoto (Awdur), Yukiko Kuru (Awdur), Masafumi Ohnishi (Awdur), Ken-ichi Sako (Awdur), Yasuhiko Ito (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2023-01-01T00:00:00Z.
• Pynciau: article
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Abstract Background Mycophenolate mofetil (MMF), a prodrug of the immunosuppressive agent mycophenolic acid (MPA), is difficult to administer because of the pharmacokinetic complexity of MPA. Although dosage adjustment according to the 12-h area under the concentration-time curve (AUC0-12) is though...