Using recombinant proteins from Lutzomyia longipalpis saliva to estimate human vector exposure in visceral Leishmaniasis endemic areas.

• Main Authors: Ana Paula Souza (Author), Bruno Bezerril Andrade (Author), Dorlene Aquino (Author), Petter Entringer (Author), José Carlos Miranda (Author), Ruan Alcantara (Author), Daniel Ruiz (Author), Manuel Soto (Author), Clarissa R Teixeira (Author), Jesus G Valenzuela (Author), Camila Indiani de Oliveira (Author), Cláudia Ida Brodskyn (Author), Manoel Barral-Netto (Author), Aldina Barral (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmania is transmitted by female sand flies and deposited together with saliva, which contains a vast repertoire of pharmacologically active molecules that contribute to the establishment of the infection. The exposure to vector saliva induces an immune response against its components that can be...