Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments

• Main Authors: Elide Zingale (Author), Angela Bonaccorso (Author), Agata Grazia D'Amico (Author), Rosamaria Lombardo (Author), Velia D'Agata (Author), Jarkko Rautio (Author), Rosario Pignatello (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies have demonstrated that Sirtuin-1 (SIRT-1)-activating molecules exert a protective role in degenerative ocular diseases. However, these molecules hardly reach the back of the eye due to poor solubility in aqueous environments and low bioavailability after topical application on the eye...