Tumoral acidosis promotes adipose tissue depletion by fostering adipocyte lipolysis

• প্রধান লেখক: Camille Lefevre (লেখক), Morgane M. Thibaut (লেখক), Audrey Loumaye (লেখক), Jean-Paul Thissen (লেখক), Audrey M. Neyrinck (লেখক), Benoit Navez (লেখক), Nathalie M. Delzenne (লেখক), Olivier Feron (লেখক), Laure B. Bindels (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective: Tumour progression drives profound alterations in host metabolism, such as adipose tissue depletion, an early event of cancer cachexia. As fatty acid consumption by cancer cells increases upon acidosis of the tumour microenvironment, we reasoned that fatty acids derived from distant adipo...