Transcriptome-Wide Effects of Sphingosine Kinases Knockdown in Metastatic Prostate and Breast Cancer Cells: Implications for Therapeutic Targeting
Sphingosine kinases 1 and 2 (SK1 and SK2) are proto-oncogenic isozymes expressed in many human tumors and associated with chemoresistance and poor prognosis. They are well-recognized therapy targets and their inhibition was shown to induce tumor volume reduction and chemosensitization in multiple ca...
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| Autores principales: | , , , |
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| Formato: | Libro |
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Frontiers Media S.A.,
2019-03-01T00:00:00Z.
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| Número de Clasificación: |
A1234.567 |
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