Breast cancer-derived DAMPs enhance cell invasion and metastasis, while nucleic acid scavengers mitigate these effects

• Main Authors: Elias O.U. Eteshola (Author), Karenia Landa (Author), Rachel E. Rempel (Author), Ibtehaj A. Naqvi (Author), E. Shelley Hwang (Author), Smita K. Nair (Author), Bruce A. Sullenger (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer (BC) is the most common malignancy in women. Particular subtypes with aggressive behavior are major contributors to poor outcomes. Triple-negative breast cancer (TNBC) is difficult to treat, pro-inflammatory, and highly metastatic. We demonstrate that TNBC cells express TLR9 and are re...